Difluorocarboxyfluorescein NHS Ester, 5-isomer (also known as Oregon Green 488 Carboxylic Acid, Succinimidyl Ester, 5-isomer) is an amine-reactive fluorinated analog of fluorescein that overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa (pKa ~ 4.7 versus 6.4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range. Although the mixed isomers of Difluorocarboxyfluorescein NHS Ester, is a preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides, purification of peptide and nucleotides labeled with 5(6) isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer usually give better resolution in HPLC purification that is often required in the conjugation processes. Difluorocarboxyfluorescein NHS Ester, 5-isomer dye structurally is identical to Invitrogens Oregon Green 488 Carboxylic Acid, Succinimidyl Ester, 5-isomer 488. Reagent grade, for research use only.

英文名：Oregon Green 488 Succinimidyl Ester

OG 488 SE

OG 488-NHS

CAS：198139-51-4

分子式：C25H13F2NO9

分子量：509.37

λabs： 496 nm

λem： 516 nm

纯度：95%

闪点：423.4±35.7 °C

密度：1.8±0.1 g/cm3

蒸汽压：0.0±2.8 mmHg at 25°C

储藏条件：-4℃下储存(1-2周)，在-20℃下储存时间更长(1-2年)

其他产品列表：

195136-52- 8 OG 488, acid

198139-51-4 OG 488, SE

195136-74-4 5-FG 488 Acid Diacetate

195136-58-4 2',7'-Difluorofluorescein

OG 488 BAPTA-1 AM

72088-94-9 5(6)-羧基荧光素(混合物); 5(6)-FAM

117548-22-8 5(6)-羧基荧光素琥珀酰亚胺酯(混合物);5(6)-FAM, SE

92557-80-7 5-羧基荧光素琥珀酰亚胺酯(单一化合物);5-FAM, SE

5(6)-羧基荧光素尸胺;5(6)-FAM cadaverine

5-羧基荧光素尸胺;5-FAM cadaverine

5-异硫氰酸荧光素尸胺;5-FITC cadaverine

5(6)-TAMRA尸胺;5(6)-TAMRA cadaverine

5-TAMRA尸胺;5-TAMRA cadaverine

6-TAMRA尸胺;6-TAMRA cadaverine