iRGD肿瘤穿透肽修饰的溶瘤腺病毒显示增强的肿瘤传导，肿瘤内传播和抗肿瘤功效基因疗法。

编号:128437

中文名称:iRGD peptide

英文名:c(CRGDKGPDC)

CAS号:1392278-76-0

单字母:H2N-CRGDKGPDC-OH(Disulfide Bridge:C1-C9)

三字母:H2N-Cys-Arg-Gly-Asp-Lys-Gly-Pro-Asp-Cys-COOH(Disulfide Bridge:Cys1-Cys9)

氨基酸个数:9

分子式:C35H57N13O14S2

平均分子量:948.04

精确分子量:947.36

等电点(PI):8.83

pH=7.0时的净电荷数:1.91

平均亲水性:1.6666666666667

疏水性值:-1.42

标签:二硫键环肽RGD、RAD肽细胞穿膜肽

10.1038/gt.2014.52iRGD tumor-penetrating peptide-modified oncolytic adenovirus shows enhanced tumor transduction, intratumoral dissemination and antitumor efficacy

10.1016/j.biopha.2017.06.103Combination of NRP1-mediated iRGD with 5-fluorouracil suppresses proliferation, migration and invasion of gastric cancer cells