今天介绍的多肽是：906480-05-5|Angiopep-2|TFFYGGSRGKRNNFKTEEY

906480-05-5|Angiopep-2|TFFYGGSRGKRNNFKTEEY

Angiopep-2 hydrochloride 是脑肽载体。抗肿瘤药物与 Angiopep-2 肽载体的结合可提高其在脑癌中的活性.

Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer[1].

编号:200599

中文名称:Angiopep-2

CAS号:906480-05-5

单字母:H2N-TFFYGGSRGKRNNFKTEEY-OH

三字母:H2N-Thr-Phe-Phe-Tyr-Gly-Gly-Ser-Arg-Gly-Lys-Arg-Asn-Asn-Phe-Lys-Thr-Glu-Glu-Tyr-COOH

氨基酸个数:19

分子式:C104H149N29O31

平均分子量:2301.47

精确分子量:2300.1

等电点(PI):10.97

pH=7.0时的净电荷数:3.98

平均亲水性:0.225

疏水性值:-1.45

储存条件:Please store the product under the recommended conditions in the Certificate of Analysis.

文献链接：

A Régina, et al. Antitumour Activity of ANG1005, a Conjugate Between Paclitaxel and the New Brain Delivery Vector Angiopep-2. Br J Pharmacol. 2008 Sep;155(2):185-97. : https://pubmed.ncbi.nlm.nih.gov/18574456