5-TAMRA Picolyl Azide,Alexa Fluor 546
产品介绍
5-TAMRA Picolyl Azide
5-TAMRA Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concen*ration of Cu(I) at the reaction site. The chelating effect of picolyl azide moiety to raise the effective concen*ration of copper at the reaction site is so great that it leads to an increase of signal intensity of up to 40-fold. In addition, the use of 5-TAMRA Picolyl Azide instead of conventional 5-TAMRA Azide allows for at least a tenfold reduction in the concen*ration of the copper catalyst without sacrificing the efficiency of labeling.
Although the mixed isomers of 5(6)-TAMRA is a preferred, routinely used red fluorescent dye for staining proteins, labeling peptides and nucleotides with TAMRA mixed isomers might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often reuired in the conjugation processes.
In summary, the in*roduction of a picolyl moiety into an azide probe leads to a substantial increase in the sensitivity of alkyne detection. This will be of special value for the detection of low abundance targets or where significant increase in signal intensity is desired.
Abs/Em Maxima

545/576
Extinction coefficient

91,000
Flow cytometry laser line

532 or 555 nm
Microscopy laser line

532 or 555 nm
Spectrally similar dyes

Alexa Fluor® 546, Atto™ 543, CF™ 555 Dye, DyLight™549
Molecular weight

808.89
CAS

N/A
Solubility

DMSO, DMF, MeOH
Purity

>97% (HPLC)
Appearance

Red solid
Storage conditions

-20C
Shipping conditions

Ambient temperature
结构式：
5-TAMRA Picolyl Azide,Alexa Fluor 546
西安瑞禧生物科技有限公司
：-
：
销售：
销售：.
炔烃 Dye alkynes
1-Ethynyl pyrene
3-Ethynyl perylene
BDP FL alkyne
FAM alkyne, 5-isomer
FAM alkyne, 6-isomer
TAMRA alkyne, 5-isomer
BDP TMR alkyne
Cyanine3 alkyne
Cyanine5 alkyne
Cyanine5.5 alkyne
Cyanine7 alkyne
Cyanine7.5 alkyne
Sulfo-Cyanine3 alkyne
Sulfo-Cyanine5 alkyne
瑞禧生物研发生产的产品有几千种，包括单分散PEG、低分散PEG、荧光染料、PROTAC / ADC Linker、核酸递送辅料、脂质体用辅料、嵌段共聚物和点击化学产品等等。这些衍生物对生物制剂、纳米颗粒、材料表面、微球、自组装和小分子具有反应性。
瑞禧生物提供定制合成功能性高分子聚合物、多肽、纳米颗粒、表面修饰与偶联、靶向纳米探针的构建、多模态多功能微纳米体系的构建以及体外诊断试剂、分子影像探针、多功能诊疗制剂等服务。

瑞禧生物从未停止过技术的拓展与创新。凭借这充满进取的创新精神，我们已经为国内外高校、科研单位、材料研究中心、生物技术制药开发公司等等定制合成了各种功能化试剂，赢得了合作单位的长期信赖。
瑞禧生物致力于为全球客户提供高性价比的助力药物递送的产品服务。公司的奋斗目标是搭建一个国际知名的药物递送修饰平台，携手高端人才和所有合作伙伴，共同为人类各行各业的事业发展做出贡献！