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Catalogue Number:C962345
Chemical Name:N-(4'-Cyano[1,1'-biphenyl]-4-yl)-N'-[4-(3H-imidazo[4,5-b]pyridin-7-yl)phenyl] Urea
Synonyms:SR-9186
CAS Number:1361414-26-7
Molecular Formula:C₂₆H₁₈N₆O
Appearance:Pale Yellow to Light Yellow Solid
Melting Point:>300°C
Molecular Weight:430.46
Storage:4°C
Solubility:Acetonitrile (Slightly), DMSO (Slightly)
Category:Standards; Enzyme Activators and Inhibitors;
Applications:N-(4'-Cyano[1,1'-biphenyl]-4-yl)-N'-[4-(3H-imidazo[4,5-b]pyridin-7-yl)phenyl] Urea, is a highly selective inhibitor of cytochrome P450 3A4, which is one of the most important enzymes involved in the metabolism of pharmaceuticals and xenobiotics.
References:Song, X., et al.: Bio. Med. Chem. Lett., 22, 1611(2012);
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