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Catalogue Number:C979195
Chemical Name:3-Cyano-2,6-dihydroxy-4-methylpyridine Potassium Salt
Synonyms:2,6-Dihydroxy-4-methyl-nicotinonitrile Potassium Salt; 2,6-Dihydroxy-3-cyano-4-methylpyridine Potassium Salt; 2,6-Dihydroxy-4-methyl-3-pyridinecarbonitrile Potassium Salt; 2,6-Dihydroxy-4-methylnicotinonitrile Potassium Salt; 3-Cyano-4-methyl-6-hydroxy-2-pyridinone Potassium Salt; 3-Cyano-4-methyl-6-hydroxy-2-pyridone Potassium Salt; 3-Cyano-6-hydroxy-4-methyl-2-pyridone Potassium Salt; NSC 19883 Potassium Salt
CAS Number:5444-02-0
Alternate CAS #
118803-30-8
Molecular Formula:C₇H₆N₂O₂K
Molecular Weight:150.13
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:3-Cyano-2,6-dihydroxy-4-methylpyridine is a synthetic human uridine phosphorylase-1 inhibitor, reduces HepG2 cell proliferation through cell cycle arrest and senescenceis and is used in the synthesis of disperse dyes. Also used in the synthesis of mGluR5 non-competitive antagonists.
References:Hallas, G. et al.: Dyes Pigments., 31, 273 (1996); Rodriguez, A. et al.: Bioorg. Med. Chem. Lett., 19; da Silva, E., et al.: Investi. New Drugs, 38, 1653(2020);
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