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Catalogue Number:C981305
Chemical Name:(2R)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(R)-(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamide
Synonyms:Bicalutamide EP Impurity E
Impurity:Bicalutamide EP Impurity E
CAS Number:1080647-25-1
Molecular Formula:C₁₈H₁₄F₄N₂O₃S
Molecular Weight:414.37
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(2R)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(R)-(4-fluorophenyl)sulfinyl]-2-hydroxy-2-methylpropanamide is an impurity of Bicalutamide, a non-steroidal peripherally active antiandrogen.
References:Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),
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