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Catalogue Number:C981370
Chemical Name:2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide
Synonyms:Teriflunomide Impurity IV
CAS Number:1385789-70-7
Molecular Formula:C₁₂H₁₂N₂O₂
Molecular Weight:216.24
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide is an impurity of Teriflunomide (A771726) which is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis.
References:Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)
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