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Catalogue Number:C982035
Chemical Name:3-(7-Cyano-5-(2-nitropropyl)indolin-1-yl)propyl Benzoate
Synonyms:1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-(2-nitropropyl)-1H-Indole-7-carbonitrile
CAS Number:350797-56-7
Molecular Formula:C₂₂H₂₃N₃O₄
Appearance:Light Yellow to Yellow Solid
Melting Point:73-75°C
Molecular Weight:393.44
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3-(7-Cyano-5-(2-nitropropyl)indolin-1-yl)propyl Benzoate is used in the preparation of Silodosin (S465000), an a1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.
References:Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995); Murata, S., et al.: J. Urol., 164, 578 (2000)
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