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Catalogue Number:C987570
Chemical Name:a-Cyclohexyl-benzeneacetic Acid
Synonyms:α-Phenyl-cyclohexaneacetic Acid; (±)-Cyclohexylphenylacetic acid; 2-Cyclohexyl-2-phenylacetic acid; Cyclohexylphenyl-acetic Acid; Cyclohexylphenylacetic acid; NSC 60418; α-Cyclohexyl-α-phenylacetic acid; α-Cyclohexylbenzeneacetic acid; α-Cyclohexylphenylacetic acid; α-Phenylcyclohexaneacetic acid
CAS Number:3894-09-5
Molecular Formula:C₁₄H₁₈O₂
Appearance:Off-White Solid
Melting Point:148-151°C
Molecular Weight:218.29
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:a-Cyclohexyl-benzeneacetic Acid is a useful synthetic intermediate. It was used as one of the reactants to prepare phenylureidobenzazepinones as cholecystokinin-B receptor antagonists. It can also be used to synthesize benzimidazole derivatives as potent AMP-activated protein kinase activators.
References:Lowe, J., et al.: J. Med. Chem., 37, 3789 (1994); Charton, J., et al.: Bioorg. Med. Chem., 14, 4490 (2006)
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