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Catalogue Number:C988063
Chemical Name:N-​Cyano-​N'-​[2-​[[(5-​methyl-​1H-​imidazol-​4-​yl)​methyl]​thio]​ethyl]​-carbamimidic Acid Methyl Ester
Synonyms:Cimetidine EP Impurity B;
Impurity:Cimetidine EP Impurity B
CAS Number:138035-55-9
Molecular Formula:C₁₀H₁₅N₅OS
Appearance:White to Off-White Solid
Melting Point:>139°C (dec.)
Molecular Weight:253.32
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-​Cyano-​N'-​[2-​[[(5-​methyl-​1H-​imidazol-​4-​yl)​methyl]​thio]​ethyl]​-carbamimidic Acid Methyl Ester which is an impurity of Cimetidine (C441650), which acts as a competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output (1).
References:1. Brimblecombe, R. et al.: J. Int. Med. Res. 1975 Mar:3(2) 86-92
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