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CAS:165108-44-1|25-​Cyclohexyl-​4'-​O-​de(2,​6-​dideoxy-​3-​O-​methyl-​a-​L-​arabino-​hexopyranosyl)​-​5-​O-​demethyl-​25-​de(1-​methylpropyl)​-Avermectin A1a

发布时间:2024-05-29 分享至:

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Catalogue Number:C988223
Chemical Name:25-​Cyclohexyl-​4'-​O-​de(2,​6-​dideoxy-​3-​O-​methyl-​a-​L-​arabino-​hexopyranosyl)​-​5-​O-​demethyl-​25-​de(1-​methylpropyl)​-Avermectin A1a
CAS Number:165108-44-1
Molecular Formula:C₄₃H₆₂O₁₁
Appearance:White to Off-White Solid
Melting Point:>153°C (dec.)
Molecular Weight:754.95
Storage:-20°C, Inert atmosphere
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:25-​Cyclohexyl-​4'-​O-​de(2,​6-​dideoxy-​3-​O-​methyl-​a-​L-​arabino-​hexopyranosyl)​-​5-​O-​demethyl-​25-​de(1-​methylpropyl)​-Avermectin A1a is an intermediate in synthesizing 22,23-Didehydro Selamectin (D439445), an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals.
References:Eshar, D., et al.: J. Am. Veterin. Med. Association., 241, 1056 (2012); Geis-Asteggiante, L., et al.: J. Chromatograph., 1258, 43 (2012)
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