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Catalogue Number:C988275
Chemical Name:N-Cyano-3-(cyanoamino)-N'-methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-imidamide (Cimetidine Impurity)
Synonyms:SKF 82964; Cimetidine EP Impurity H
Impurity:Cimetidine EP Impurity H
CAS Number:74886-59-2
Molecular Formula:C₁₀H₁₈N₈S₂
Appearance:White to Off-White Solid
Melting Point:>171°C (dec.)
Molecular Weight:314.43
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Cyano-3-(cyanoamino)-N'-methyl-7,8-dithia-2,4,11-triazadodec-2-en-12-imidamide (Cimetidine EP Impurity H) is an impurity of Cimetidine (C441650), an H2-receptor antagonist that is used for the treatment and prevention of stress-induced gastroduodenal lesions.
References:Burland, W., et al.: Brit. J. Clin. Pharm., 2, 481 (1975); Kauffman, G. & Morton, I.: Gastroenterology, 75, 1099 (1978); Peura, D. & Johnson, L.: Ann. Int. Med., 103, 173 (1985)
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