试剂家(www.empireagents.com) - 瑞禧生物旗下试剂品牌。致力于为全球客户提供高性价比的助力药物递送的产品服务。公司的奋斗目标是搭建一个国际知名的药物递送修饰平台，携手高端人才和所有合作伙伴，共同为人类各行各业的事业发展做出贡献！
Catalogue Number:C988365
Chemical Name:11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
Synonyms:12-Hydroxy Nevirapine;
CAS Number:133627-24-4
Molecular Formula:C₁₅H₁₄N₄O₂
Appearance:Pale Yellow to Light Brown Solid
Melting Point:>184ºC (dec.)
Molecular Weight:282.3
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Benzodiazepines;
Applications:11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, is a metabolite of Nevirapine (N391275), which is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. It is also an antiviral.
References:Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991), Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1993), Guay, L.A., et al.: Lancet, 354, 795 (1999),
试剂家(www.empireagents.com)从未停止过技术的拓展与创新。凭借这充满进取的创新精神，我们已经为国内外高校、科研单位、材料研究中心、生物技术制药开发公司等等定制合成了各种功能化试剂，赢得了合作单位的长期信赖。
更多产品推荐:
CAS:1079389-44-8|Agomelatine-d4
CAS:1079389-42-6|Agomelatine-d6
CAS:1385018-58-5|Agomelatine Dimer Acetamide
CAS:185421-27-6|Agomelatine Dimer Urea
CAS:548-42-5|Agroclavine
CAS:124478-60-0|Aglepristone
CAS:2598-30-3|8-Hydroxyquinoline-5-carbaldehyde
CAS:2641256-91-7|(1S,2S,3R,4R)-3-((R)-1-Acetamido-2-ethylbutyl)-4-amino-2-hydroxycyclopentane-1-carboxylic Acid
CAS:2758048-73-4|(1S,2S,3R,4R)-3-((S)-1-Acetamido-2-ethylbutyl)-2-acetoxy-4-guanidinocyclopentane-1-carboxylic Acid
CAS:2580100-34-9|(2S)​-​2-​Amino-​3-​(2-​hydroxy-​1H-​imidazol-​4-​yl)​propanoic Acid Hydrochloride