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Catalogue Number:C988500
Chemical Name:8-Cyclopentyl-1,3-dipropylxanthine
Synonyms:8-Cyclopentyl-3,9-dihydro-1,3-dipropyl-1H-purine-2,6-dione; DPCPX, PD 116,948
CAS Number:102146-07-6
Molecular Formula:C₁₆H₂₄N₄O₂
Appearance:White to Off-White Solid
Melting Point:194 - 197°C
Molecular Weight:304.39
Storage:-20°C
Solubility:Chloroform (Sparingly), Ethyl Acetate (Slightly, Heated, Sonicated), Methanol (S
Category:Standards; Enzyme Activators and Inhibitors; Neurochemicals;
Applications:DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist.
References:Gessi, S., et al.: Mol. Pharmacol., 67, 2137 (2005), Minor, T.R., et al.: Behav. Neurosci., 122, 1236 (2008), Gracia, E., et al.: J. Neurochem., 107, 161 (2008), Gessi, S., et al.: Biochem. Pharmacol., 75, 562 (2008),
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