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Catalogue Number:D229205
Chemical Name:Deguelin
Synonyms:(7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one; (-)-Deguelin; (-)-cis-Deguelin;
CAS Number:522-17-8
Molecular Formula:C₂₃H₂₂O₆
Appearance:Off-White to Pale Yellow Solid
Melting Point:>90°C (dec.)
Molecular Weight:394.42
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Light Sensitive
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Deguelin exhibits potent apoptotic and antiangiogenic activities in a variety of transformed cells and cancer cells. Deguelin also exhibits potent tumor suppressive effects in xenograft tumor models for many human cancers.
References:Chang, D.J.. et al.: J. Med. Chem., 55, 10863 (2012);
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