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CAS:170570-75-9|Dehydroxy Bromocelecoxib

发布时间:2024-05-31 分享至:

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Catalogue Number:D229260
Chemical Name:Dehydroxy Bromocelecoxib
Synonyms:4-[5-[4-(Bromomethyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide
CAS Number:170570-75-9
Molecular Formula:C₁₇H₁₃BrF₃N₃O₂S
Appearance:Off-White Solid
Molecular Weight:460.27
Solubility:Chloroform, DCM
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Dehydroxy Bromocelecoxib is an intermediate in the synthesis of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor with known anti-inflammatory properties.
References:Abdellatif, K.R.A., et al.: Bioorg. Med. Chem., 17, 5182 (2009); Desai, D., et al.: Chemico-Bio. Interact., 188, 446 (2010)
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