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Catalogue Number:D229405
Chemical Name:20,21-Dehydro Spironolactone
Synonyms:(7α,17α)-7-(Acetylthio)-17-hydroxy-3-oxo-pregna-4,20-diene-21-carboxylic Acid γ-Lactone;
Impurity:Spironolactone EP Impurity A
CAS Number:132458-33-4
Molecular Formula:C₂₄H₃₀O₄S
Appearance:White to Off-White Solid
Melting Point:205-208°C
Molecular Weight:414.56
Storage:-20°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:20,21-Dehydro Spironolactone (Spironolactone EP Impurity A) is an impurity of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.
References:Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),
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