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CAS:122852-86-2|3,4-Didehydro Alosetron

发布时间:2024-05-31 分享至:

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Catalogue Number:D229435
Chemical Name:3,4-Didehydro Alosetron
Synonyms:2,5-Dihydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one; 2,5-Dihydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1-one; Alosetron 3,4-Didehydro Impurity:Impurity:Alosetron 3,4-Didehydro Impurity:CAS Number:122852-86-2
Molecular Formula:C₁₇H₁₆N₄O
Molecular Weight:292.34
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:3,4-Didehydro Alosetron is an impurity of Alosetron (A575500, HCl salt) which is a serotonin 5HT3-receptor antagonist used in treatment of irritable bowel syndrome.
References:Camilleri, M., et al.: Lancet, 355, 1035 (2000); Nestorov, I., et al.: Drug Metab. Dispos., 30, 276 (2002); Lewis, D., et al.: Drug Metab. Rev., 35, 1 (2003); Tang, H., et al.: J. Pharm. Sci., 95, 1783 (2006); Gleeson, M., et al.: J. Med. Chem., 50, 101 (2007),
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