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Catalogue Number:D229500
Chemical Name:3,4-Dehydro Cilostazol
Synonyms:6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-2(1H)-quinolinone;
Impurity:Cilostazol USP Related Compound B
CAS Number:73963-62-9
Molecular Formula:C₂₀H₂₅N₅O₂
Appearance:White to Beige Solid
Melting Point:179-180°C
Molecular Weight:367.44
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A metabolite of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogenic, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo. Neuroprotective & Neuroresearch product.
References:Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998), Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999), Tsuchikane, E., et al.: Circulation, 100, 21 (1999),
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