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Catalogue Number:D229505
Chemical Name:∆9,11-Dehydro-17a-cyanomethyl Estradiol
Synonyms:(17α)-3,17-Dihydroxy-19-norpregna-1,3,5(10),9(11)-tetraene-21-nitrile; 17α-Cyanomethylestra-1,3,5(10),9(11)-tetraene-3,17β-diol; STS 825
CAS Number:86153-38-0
Molecular Formula:C₂₀H₂₃NO₂
Appearance:White to Off-White Solid
Melting Point:228 - 233°C
Molecular Weight:309.4
Storage:-20°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly, Sonicated)
Category:Research Tools;
Applications:∆9,11-Dehydro-17a-cyanomethyl estradiol is a metabolite of progestin dienogest (D441870), and is currently being investigated for progesterone-receptor binding, progestational, antiprogestational, estrogenic and antigonadotropic activities for the inhibition of fertility. It is also being considered a novel treatment for heavy menstrual bleeding.
References:Oettel, M., et al.: Pharmazie, 41, 627 (1993); Kiley, J. & Shulman, L.: Int. J. Womens Health, 3, 281 (2011);
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