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CAS:752188-68-4|4-Dehydroxy-2-hydroxy Olsalazine

发布时间:2024-05-31 分享至:

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Catalogue Number:D229865
Chemical Name:4-Dehydroxy-2-hydroxy Olsalazine
Synonyms:3-[2-(3-Carboxy-4-hydroxyphenyl)diazenyl]-2-hydroxy-benzoic Acid; 3-[(3-Carboxy-4-hydroxyphenyl)azo]-2-hydroxy-benzoic Acid
CAS Number:752188-68-4
Molecular Formula:C₁₄H₁₀N₂O₆
Appearance:Orange to Brown Solid
Melting Point:256-258°C
Molecular Weight:302.24
Storage:-20°C, Light sensitive, Light sensitive
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Dehydroxy-2-hydroxy Olsalazine is an impurity of Olsalazine sodium salt (O586000). Olsalazine Sodium Salt is a dimer of Mesalazine (M258100), an anti-inflammatory drug used in the treatment of inflammatory bowel disease and ulcerative colitis.
References:Willoughby, C.P., Gut, 23. 1081 (1982), Scand, J., et al.: Gastroenterol, 20, 607 (1985), Wadworth, A.N., et al.: Drugs, 41, 647 (1991)
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