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CAS:1105067-93-3|(2E)-2,3-Dehydroxy Atorvastatin

发布时间:2024-05-31 分享至:

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Catalogue Number:D230045
Chemical Name:(2E)-2,3-Dehydroxy Atorvastatin
Synonyms:(2E,5S)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-2-heptenoic Acid; Atorvastatin 3-Deoxy-hept-2-enoic Acid; Sodium Salt (USP);
Impurity:Atorvastatin 3-Deoxy-hept-2-enoic Acid Sodium Salt (USP)
CAS Number:1105067-93-3
Molecular Formula:C₃₃H₃₃FN₂O₄
Appearance:White to Pale Beige Solid
Melting Point:>78°C (dec.)
Molecular Weight:540.64
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(2E)-2,3-Dehydroxy Atorvastatin (Atorvastatin 3-Deoxy-hept-2-enoic Acid Sodium Salt (USP)) is an impurity in the synthesis of Atorvastatin (A791750).
References:Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996);
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