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Catalogue Number:D230095
Chemical Name:Dehydrosertindole
Synonyms:1-[2-[4-[5-Chloro-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl]ethyl]-1,3-dihydro-2H-Imidazol-2-one; Lu 28-092
CAS Number:173294-84-3
Molecular Formula:C₂₄H₂₄ClFN₄O
Molecular Weight:438.92
Category:Research Tools;
Applications:Dehydrosertindole is a metabolite of Sertindole (S279500), an antipsychotic agent that is used to treat patients with schizophrenia. Dehydrosertindole inhibits limbic dopamine function and has high affinity for dopamine D2 receptors, serotonin 5-hydroxytryptamine (5-HT) 2 receptors and α1-adrenergic receptors.
References:Canal-Raffin, M., et al.: J. Chromatogr. B, 814, 61 (2005); Daniel, D., et al.: Psychopharmacol. Bull., 34, 61 (1998); Dunn, C. & Fitton, A.: CNS Drugs, 5, 224 (1996)
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