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Catalogue Number:D230150
Chemical Name:N-Dehydroxyzileuton
Synonyms:N-(1-Benzo[b]thien-2-ylethyl)urea; (1-Benzo[b]thien-2-ylethyl)urea; A 66193; Abbott 66193; USP Zileuton Related Compound A;
CAS Number:171370-49-3
Molecular Formula:C₁₁H₁₂N₂OS
Appearance:White to Off-White Solid
Melting Point:201-203°C
Molecular Weight:220.29
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Dehydroxyzileuton is a pharmacologically inactive metabolite of Zileuton (Z420000), an inhibitor of 5-lipoxygenase that is used to treat patients with asthma.
References:Awni, W., et al.: Clin. Pharm., 29, 62 (1995); Machinist, J., et al.: Clin. Pharm., 29, 34 (1995); Remko, M., et al.: Phys. Chem. Chem. Phys., 2, 2511 (2000);
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