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Catalogue Number:D230285
Chemical Name:5-Dehydroxy (3S)-Atorvastatin
Synonyms:(δS)-2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid;
CAS Number:887196-26-1
Molecular Formula:C₃₃H₃₅FN₂O₄
Molecular Weight:542.64
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Dehydroxy (3S)-Atorvastatin is an impurity of Atorvastatin (A791750), which is a drug used for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor.
References:Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000);
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