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Catalogue Number:D230308
Chemical Name:11-Dehydro-6b,17-dihydroxy-corticosterone 21-Acetate
Synonyms:6β,17,21-Trihydroxy-pregn-4-ene-3,11,20-trione 21-Acetate; NSC 15477; 2-((6R,8S,9S,10R,13S,14S,17R)-6,17-Dihydroxy-10,13-dimethyl-3,11-dioxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Acetate
CAS Number:13096-52-1
Molecular Formula:C₂₃H₃₀O₇
Appearance:Off-white Solid
Molecular Weight:418.48
Solubility:Acetone, Methanol
Category:Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:11-Dehydro-6b,17-dihydroxy-corticosterone 21-Acetate is an intermediate in the synthesis of 6b-Hydroxycortisone (H918450). 6b-Hydroxycortisone can be used as a probe to detect inhibition of CYP3A4 in vivo.
References:Peng, C.C., et. al.: Clin. Pharmacol. Ther., 89, 888 (2011)
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