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Catalogue Number:D230310
Chemical Name:Dehydronitrosonisoldipine
Synonyms:2,6-Dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylic Acid 3-Methyl 5-(2-Methylpropyl) Ester; 2,6-Dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylic Acid Methyl 2-Methylpropyl Ester; 5-Methyl 3-(2-Methylprop-3-yl) 2,6-Dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicarboxylate; Nisoldipine Impurity D
Impurity:Nisoldipine
CAS Number:87375-91-5
Molecular Formula:C₂₀H₂₂N₂O₅
Appearance:Light Green to Light Blue Solid
Molecular Weight:370.4
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Light Sensitive
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Dehydronitrosonisoldipine is an impurity of Nisoldipine (N489125). Nisoldipine is a dihydropyridine calcium channel blocker and it is antihypertensive and antianginal.
References:Kazda, S., et al.: Arzneimittel-Forsch., 30, 2144 (1980); Pasanisi, F., et al.: Eur. J. Clin. Pharmacol., 29, 21 (1985); Lam, J., et al.: J. Am. Col. Cardiol., 6, 447 (1985)
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