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Catalogue Number:D230350
Chemical Name:5-Dehydro Tolvaptan
Synonyms:N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide; 1H-1-Benzazepine, Benzamide Deriv.; 7-Chloro-1-[2-methyl-4-[(2-methylbenzoyl)amino]benzoyl]-5-Oxo-2,3,4,5-tetrahydro-1H-1-benzazepine
CAS Number:137973-76-3
Molecular Formula:C₂₆H₂₃ClN₂O₃
Appearance:White to Off-White Solid
Melting Point:>118°C (dec.)
Molecular Weight:446.93
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:5-Dehydro Tolvaptan is an impurity of Tolvaptan (T536650), a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH g
References:Yin, L., et al.: Tetrahedron, Asym., 21, 2390 (2010); Torisawa, Y., et al.: Bioorg. Med. Chem. Lett., 17, 6455 (2007); Kondo, K., et al.: Bioorg. Med. Chem., 7, 1743 (1999);
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