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Catalogue Number:D230660
Chemical Name:Delamanid
Synonyms:(2R)-2,3-Dihydro-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]phenoxy]methyl]-imidazo[2,1-b]oxazole; OPC 67683
CAS Number:681492-22-8
Molecular Formula:C₂₅H₂₅F₃N₄O₆
Appearance:White to Light Beige Solid
Melting Point:>189°C (dec.)
Molecular Weight:534.48
Storage:-20°C
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Delamanid is a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
References:Gler, M.T., et al.: New Engl. J. Med., 366, 2151 (2012); Skripconoka, V., et al.: Eur. Respir. J., 41, 1393 (2012); Diacon, A.H., et al.: Int. J. Tuberc. Lung D., 15, 949 (2011); Zhang, Q., et al.: Cell Biochem. Biophys., 67, 957 (2013)
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