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Catalogue Number:D230725
Chemical Name:Demeclocycline Hydrochloride
Synonyms:[4S-(4α,4aα,5aα,6β,12aα)]-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride; 6-Demethyl-7-chlorotetracycline Hydrochloride; Demetraciclina; Detravis; Ledermycin Hydrochloride; Meciclin;
CAS Number:64-73-3
Alternate CAS #
Free base: 127-33-3
Molecular Formula:C₂₁H₂₂Cl₂N₂O₈
Appearance:Light Yellow to Yellow Solid
Melting Point:>192°C (dec.)
Molecular Weight:501.31
Storage:-20°C
Solubility:0.1N H2SO4 (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Category:Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
Applications:An antibiotic related to tetracycline and produced by streptomyces aureofaciens. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.This compound is a contaminant of emerging concern (CECs).
References:Jilka, R., et al.: J. Clin. Invest., 104, 439 (1999), Hauge, E; Bone, 28, 556
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