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Catalogue Number:D230822
Chemical Name:rac O-Demethyl Ambrisentan
Synonyms:2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-hydroxy-3,3-diphenylpropanoic Acid;
CAS Number:1106685-85-1
Molecular Formula:C₂₁H₂₀N₂O₄
Molecular Weight:364.39
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:rac O-Demethyl Ambrisentan is a derivative of Ambristentan (A575860). Ambristentan is a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.
References:Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),
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