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Catalogue Number:D230880
Chemical Name:2-Demethyl Colchicine
Synonyms:N-[(7S)-5,6,7,9-Tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; O2-Demethylcolchicine; (-)-2-Demethylcolchicine;NSC 180533;
CAS Number:102491-80-5
Molecular Formula:C₂₁H₂₃NO₆
Appearance:Yellow Solid
Melting Point:166 - 168°C (dec.)
Molecular Weight:385.41
Storage:-20°C
Solubility:Chloroform (Slightly, Sonicated), Methanol
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A metabolite of Colchicine (C640000). Has shown anti-tumor activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:Martinez, M., et al.: J. Appl. Toxicol., 15, 49 (1995), De Vincenzo, R., et al.: Oncol. Res., 11, 145(1999), Das, D., et al.: Biochim. Biophys. Acta., 1502, 351 (2000), Wagner, B., et al.: J. Biol. Chem., 275, 22461(2000),
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