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Catalogue Number:D231005
Chemical Name:4-Demethyltrimethoprim
Synonyms:4-[(2,4-Diamino-5-pyrimidinyl)methyl]-2,6-dimethoxyphenol; α-(2,4-Diamino-5-pyrimidinyl)-2,6-dimethoxy-p-cresol; 2,4-Diamino-5-(3,5-dimethoxy-4-hydroxybenzyl)pyrimidine; 2,4-Diamino-5-(4-hydroxy-3,5-dimethoxybenzyl)pyrimidine; 4'-Hydroxytrimethoprim; Ro 5-9552/001
CAS Number:21253-58-7
Molecular Formula:C₁₃H₁₆N₄O₃
Appearance:Off-White to Beige Solid
Melting Point:>188°C (dec.)
Molecular Weight:276.29
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:4-Demethyltrimethoprim is an impurity of Trimethoprim (T795615), an antibacterial agent.
References:Mengelers, M.J.B., et al.: J. Vetern. Pharmacol. Therap., 20, 24 (1997); Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),
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