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Catalogue Number:D231035
Chemical Name:N-Demethyl-3,4-dihydroxytamoxifen Hydrochloride(Z,E mixture)
Synonyms:4-[(Z,E)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-1,2-benzenediol Hydrochloride
CAS Number:2125720-11-6
Alternate CAS #
Free Base: 2125720-10-5
Molecular Formula:C₂₅H₂₈ClNO₃
Appearance:Light Orange to Orange Solid
Melting Point:163 - 165°C
Molecular Weight:425.95
Storage:-20°C, Inert atmosphere
Solubility:Methanol (Slightly), Water (Slightly, Heated)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Demethyl-3,4-dihydroxytamoxifen is an metabolite of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor.
References:Zhang, F., et al.: Chem. Rs. Toxicol., 13, 53 (2000); Sutherland, R., et al.: Nature, 267, 434
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