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Catalogue Number:D231260
Chemical Name:Demethylpiperazinyl 7-Desoxo 7-Thioxosildenafil Sulfonic Acid
Synonyms:4-Ethoxy-3-(1-methyl-3-propyl-7-thioxo-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonic Acid
Impurity:Sildenafil Impurity:CAS Number:1353018-10-6
Molecular Formula:C₁₇H₂₀N₄O₄S₂
Appearance:Off-White to Yellow Solid
Melting Point:>155°C
Molecular Weight:408.5
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly, Sonicated)
Stability
Hygroscopic
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Demethylpiperazinyl 7-Desoxo 7-Thioxosildenafil Sulfonic Acid is an impurity of Sildenafil Citrate (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.
References:Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996), Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998), Vaysse, J. et al.: J. Pharm. Biomed. Anal., 59, 58 (2012);
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