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Catalogue Number:D231295
Chemical Name:Demethyl Propionitrile Isradipine
Synonyms:4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid 3-(2-Cyanoethyl) 5-(1-Methylethyl) Ester; 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid 2-Cyanoethyl 1-Methylethyl Ester; (±)-4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-5-pyridinedicarboxylic Acid 2-Cyanoethyl 1-Methylethyl Ester; 2,1,3-Benzoxadiazole 3,5-Pyridinedicarboxylic Acid Derivative
CAS Number:88977-31-5
Molecular Formula:C₂₁H₂₂N₄O₅
Appearance:Yellow to Brown Solid
Melting Point:>35°C
Molecular Weight:410.42
Storage:-20°C, Inert atmosphere, Light sensitive
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Sensitive to Air, Sensitive To Air
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Demethyl Propionitrile Isradipine is an intermediate in the synthesis of Isradipine (I925000), a dihydropyridine calcium channel blocker. Antihypertensive
References:Nelson, E.B., et al.: Clin. Pharmacol. Ther., 40, 694 (1986); Hof, R.P., et al.: J. Cardiovasc. Pharmacol., 8, 221 (1986)
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