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Catalogue Number:D231355
Chemical Name:N-Demethyl Vandetanib
Synonyms:N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(4-piperidinylmethoxy)-4-quinazolinamine; 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(piperidin-4-yl)methoxy]quinazoline;
CAS Number:338992-12-4
Molecular Formula:C₂₁H₂₂BrFN₄O₂
Appearance:Pale Yellow to Light Yellow Solid
Melting Point:>170°C (dec.)
Molecular Weight:461.33
Storage:4°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A major metabolite of Vandetanib (V097100).
References:Gustafson, D.L. et al.: J. Pharmacol. Exp. Therap., 318, 872 (2006); Weil, A. et al.: Clin. Pharmakin., 49, 607 (2010); Stephen, R. et al.: J. Med. Chem., 45, 1300 (2002);
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