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Catalogue Number:D231545
Chemical Name:Demethoxy Aliskiren Fumarate (2:1)
Synonyms:(αS,γS,δS,ζS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-3-(3-methoxypropoxy)-α,ζ-bis(1-methylethyl)benzeneoctanamide (2E)-2-Butenedioate (2:1)
CAS Number:1438401-07-0
Alternate CAS #
Free Base: 1438401-06-9
Molecular Formula:C₆₂H₁₀₆N₆O₁₄
Molecular Weight:1159.54
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Demethoxy Aliskiren Fumarate (2:1) is an impurity of Aliskiren (A536000), an orally active, synthetic nonpeptide renin inhibitor. Antihypertensive.
References:Molleti, S., et. al.: Pharma Chemica, 5, 174 (2013); Lefevre, G., et al.: J. Immunoassay, 21, 65 (2000); Allikments, K., et al.: Curr. Opin. Invest. Drugs, 3, 1479 (2002); Wood; J.M., et al.: Biochem. Biophys. Res. Commun., 308, 698 (2003); Grandman, A.H., et al.: Circulation, 111, 1012 (2005)
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