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Catalogue Number:D231595
Chemical Name:O-Demethyl Lenvatinib
Synonyms:4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-hydroxy-6-quinolinecarboxamide; Lenvatinib M2
CAS Number:417717-04-5
Molecular Formula:C₂₀H₁₇ClN₄O₄
Molecular Weight:412.83
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:O-Demethyl Lenvatinib is a metabolite of Lenvatinib (L329400) which is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.
References:Matsui, J., et al.: Clin. Cancer Res., 14, 5459 (2008); Gild, M., et al.: Nature Rev. Endocrinol., 7, 617 (2011)
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