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Catalogue Number:D231635
Chemical Name:27-Deoxyactein
Synonyms:(3β,12β,16β,23S,24R,25R)-12-(Acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-ylβ-D-Xylopyranoside; 26-Deoxyactein; 27-Deoxyactein
CAS Number:264624-38-6
Molecular Formula:C₃₇H₅₆O₁₀
Appearance:White to Off-White Solid
Melting Point:>204°C (dec.)
Molecular Weight:660.83
Storage:-20°C, Hygroscopic
Solubility:Chloroform (Slightly), Methanol (Very Slightly), Pyridine (Slightly)
Stability
Hygroscopic
Category:Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:27-Deoxyactein has shown stimulation of osteoblast function and inhibits bone resorbing mediators in the treatment of osteoporosis. It is a derivative of Actein (A191800), a gamma secretase modulators derived from botanicals.
References:Choi, E. et al. J. App. Toxicol., 33, 190 (2010); Findeis, M. et al.: ACS. Chem. Neurosci., 3, 941 (2012); Einbond, L. et al.: Fund. Clin. Pharm., 23, 311 (2009);
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