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Catalogue Number:D231650
Chemical Name:Demethyl Lenvatinib Quinolone
Synonyms:4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-1,2-dihydro-7-hydroxy-2-oxo-6-quinolinecarboxamide; Lenvatinib Metabolite M2’
CAS Number:1788901-76-7
Molecular Formula:C₂₀H₁₇ClN₄O₅
Molecular Weight:428.83
Category:Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Demethyl Lenvatinib Quinolone is a metabolite of Lenvatinib (L329400) which is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.
References:Matsui, J., et al.: Clin. Cancer Res., 14, 5459 (2008); Gild, M., et al.: Nature Rev. Endocrinol., 7, 617 (2011)
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