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Catalogue Number:D232530
Chemical Name:3-Deoxy-3-chloroabiraterone (Mixture of Diastereomers)
Synonyms:3-​(3-Chloroandrosta-​5,​16-​dien-​17-​yl)​-pyridine; 3-((8R,9S,10R,13S,14S)-3-Chloro-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine (Mixture of Diastereomers)
CAS Number:2484719-16-4
Molecular Formula:C₂₄H₃₀ClN
Molecular Weight:367.95
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Steroids;
Applications:3-Deoxy-3-chloroabiraterone is an impurtiy of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)
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