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Catalogue Number:A173785
Chemical Name:(16b)-21-(Acetyloxy)-2'-methyl-5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,11,20-trione
Synonyms:21-Hydroxy-2'-methyl-5'βH-Pregna-1,4-dieno[17,16-d]oxazole-3,11,20-trione Acetate (Ester); Deflazacort Impurity;
Impurity:Deflazacort Impurity:CAS Number:13649-84-8
Molecular Formula:C₂₅H₂₉NO₆
Appearance:Off-White Solid
Melting Point:179-180°C
Molecular Weight:439.5
Storage:-20°C
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly)
Category:Standards; Steroids;
Applications:(16b)-21-(Acetyloxy)-2'-methyl-5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,11,20-trione, is an impurity of Deflazacort (D228975), a systemic corticosteroid, and a derivative of prednisolone. Used for rheumatoid arthritis and lupus.
References:Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984),
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