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CAS:190448-56-7|3-O-Acetyl Ezetimibe 2,3,4-Tri-O-acetyl-b-D-glucuronide Methyl Ester

发布时间:2024-06-05 分享至:

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Catalogue Number:A173800
Chemical Name:3-O-Acetyl Ezetimibe 2,3,4-Tri-O-acetyl-b-D-glucuronide Methyl Ester
Synonyms:4-[(2S,3R)-3-[(3S)-3-(Acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-fluorophenyl)-4-oxo-2-azetidinyl]phenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate
CAS Number:190448-56-7
Molecular Formula:C₃₉H₃₉F₂NO₁₃
Appearance:White to Off-White Solid
Melting Point:>79°C (dec.)
Molecular Weight:767.72
Storage:-20°C
Solubility:Chloroform (Slightly), DMSO (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Intermediate in the preparation of Phase-II metabolites of Ezetimibe. Glucuronide azetidinone cholesterol absorption inhibitor.
References:Mutlib, A., et al.: Drug Metab. Dispos., 20, 451 (1992),
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