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CAS:1959572-98-5|2-[(1-Acetyl-1H-indazol-6-yl)sulfinyl]-N-methylbenzamide

发布时间:2024-06-05 分享至:

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Catalogue Number:A179314
Chemical Name:2-[(1-Acetyl-1H-indazol-6-yl)sulfinyl]-N-methylbenzamide
Synonyms:Axitinib Impurity D
CAS Number:1959572-98-5
Molecular Formula:C₁₇H₁₅N₃O₃S
Appearance:White to Off-White Solid
Melting Point:239 - 240°C
Molecular Weight:341.38
Storage:4°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly, Heated)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-[(1-Acetyl-1H-indazol-6-yl)sulfinyl]-N-methylbenzamide is an impurity of Axitinib (A794650). Axitinib is a tyrosine kinase inhibitor. Axitinib is also used in cancer therapy.
References:Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003),
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