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Catalogue Number:A185035
Chemical Name:N-Acetyl-L-(-)-leucine
Synonyms:(S)-2-Acetamido-4-methylpentanoic Acid; Acetyl-L-leucine; Acetylleucine; N-Acetyl-L-leucine; N-Acetylleucine; NSC 206316
CAS Number:1188-21-2
Molecular Formula:C₈H₁₅NO₃
Appearance:White to Off-White Solid
Melting Point:174-175°C
Molecular Weight:173.21
Storage:4°C
Solubility:DMSO (Slightly), Ethanol (Slightly), Water (Slightly), Methanol (Slightly)
Category:Building Blocks; Miscellaneous;
Applications:N-Acetyl-L-(-)-leucine is used in the preparation of small molecule inhibitors of anti-apoptotic Bcl-2 family proteins. Also used in the preparation of amphiphilic copolymers involving hydrophobic amino acid and oligopeptide side chains for optical tumor imaging in vivo.
References:Zheng, C. et al.: Bioorg. Med. Chem. Lett., 22, 39 (2012); Miki, K. et al.: Bull. Chem. Soc. Jap., 85, 1277 (2012);
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