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Catalogue Number:A187160
Chemical Name:4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide
CAS Number:1204329-34-9
Molecular Formula:C₁₆H₁₉F₃N₄O₂
Molecular Weight:356.34
Category:Standards; Enzyme Activators and Inhibitors;
Applications:4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1), a ubiquitously expressed transmembrane ion channel that regulates intracellular pH.
References:Huber, J. D., et al.: J. Med. Chem. 55, 7114 (2012); Kilic, A., et al.: J. Pharm. Exp. Ther. 351, 492 (2014)
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