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CAS:1304788-26-8|(4S)-9-(Acetyloxy)-10-[(acetyloxy)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

发布时间:2024-06-05 分享至:

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Catalogue Number:A187865
Chemical Name:(4S)-9-(Acetyloxy)-10-[(acetyloxy)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
CAS Number:1304788-26-8
Molecular Formula:C₂₅H₂₂N₂O₈
Appearance:Yellow Solid
Molecular Weight:478.45
Solubility:DMSO, Methanol, Water
Category:Building Blocks; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:(4S)-9-(Acetyloxy)-10-[(acetyloxy)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione is an intermediate in the synthesis of Camptothecin analogs for the inhibition of topoisomerase I and antitumor activity.
References:Kingsbury, W.D., J. Med. Chem., 34, 98 (1991);
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