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Catalogue Number:A188150
Chemical Name:N-Acetylprocainamide Hydrochloride
Synonyms:4'-[[2-(Diethylamino)ethyl]carbamoyl]-acetanilide Monohydrochloride; 4-(Acetylamino)-N-[2-(diethylamino)ethyl]-benzamide Monohydrochloride; Acecainide Hydrochloride; ASL 601
CAS Number:34118-92-8
Alternate CAS #
Free Base: 32795-44-1
Molecular Formula:C₁₅H₂₄ClN₃O₂
Appearance:Pale Beige to Beige Solid
Melting Point:>182°C (dec.)
Molecular Weight:313.82
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Very Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Acetylprocainamide Hydrochloride is an antiarrhythmic agent and a metabolite of Procainamide (P755130). Procainamide is a drug used for both supraventricular and ventricular arrhythmias. For example, it can be used to convert new-onset atrial fibrillation, though it is suboptimal for this purpose. It can also be used to treat Wolff-Parkinson-White syndrome by prolonging the refractory period of the accessory pathway.
References:Fenster, P., et al.: Am. Heart J.. 106, 501(1983); Sellers Jr, T. et al.: Circulation 55, 15 (1983)
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